Steven Denning recently wrote in Forbes that fifty years ago, the life expectancy of a Fortune 500 enterprise was approximately 75 years. Today, it's less than 15 years and on the decline. How can large enterprises adopt lean Startup principles and stay relevant by creating meaningful and sustainable innovation? Representatives from Accenture Studios (https://www.accenture.com/us-en/innovation-architecture-accenture-studios) will share their keys to success and barriers to forming a successful innovation mindset and ‘startup culture’ within large organizations? When the Enterprise immune system attacks change, there are ways to fight back. Enterprises who wish to tap into the creativity and innovation of smaller companies should start acting like them.